吉藤 元　講師

吉藤 元　講師

dr_yoshifuji_s
  • 吉藤　元　（よしふじ　はじめ）
  • 石川県金沢市出身

■研究主題

・患者サンプルを用いた多層的解析による自己免疫疾患の病因・病態の解明

・高安動脈炎など血管炎症候群の病因・病態の解明および治療法の改良

・IgG4関連疾患の病因・病態の解明および治療法の改良

■資格

1997年 5月 6日 医師免許（第389463号）

2000年 9月22日 日本内科学会認定医（第17398号）

2005年11月24日 京都大学医学博士（第2918号）

2006年 3月 1日 日本リウマチ学会専門医（第4250号）

2016年12月16日 日本内科学会総合内科専門医（第24124号）

2018年 2月14日 日本臨床免疫学会免疫療法認定医（JSCI-NI-0108）

■所属学会

日本内科学会：　1997年5月14日～　指導医（2007年9月1日～）

日本リウマチ学会：　2001年1月11日～　評議員（2011年7月18日～）　指導医（第1978号，2015年3月1日～）　International Scientific Committee Member（2019年8月9日～）

日本IgG4関連疾患学会：　2014年～　理事（2019年9月1日～）

日本シェーグレン症候群学会：　2005年～　理事（2022年9月18日～）

日本肺高血圧・肺循環学会：　2016年4月1日～　評議員（2016年4月1日～）　第8回学術集会・副会長（2023年6月3日～4日）

日本臨床免疫学会：　2004年1月1日～　評議員（2020年1月1日～）

米国リウマチ学会：　2019年9月5日～　International Member（2019年9月5日～）

日本免疫学会：　2001年～

日本炎症・再生医学会：　2013年3月26日～

■受賞歴

Modern Rheumatology Case Report Top Reviewer Award 2020　2021年2月15日　日本リウマチ学会より受賞

Modern Rheumatology Top Reviewer Award 2020　2021年2月17日　日本リウマチ学会より受賞

Modern Rheumatology Case Report Top Reviewer Award 2022　2023年2月10日　日本リウマチ学会より受賞

Circulation Journal Award 2024 Clinical Investigation部門 優秀賞　2025年1月22日　日本循環器学会より受賞

■社会における活動

・ＨＯＲＰ（再発性多発軟骨炎患者会）：　顧問（2014年4月7日～）

・あけぼの会（高安動脈炎患者会）：　オブザーバー（2005年9月10日～2019年2月27日；会自体が休止中）

■ひとこと

私たちのチームの使命は、希少難病である全身性自己免疫疾患の患者さんが正確かつ迅速に診断され、効果的な治療を受けられる医療環境を整えることです。そして、医療者、家族、行政、さらには社会全体が患者さんを支える仕組みづくりを目指しています。複数施設の研究者と連携し、臨床研究と基礎研究を融合させた成果を世界に発信し続けています。

また、私は高安動脈炎や再発性多発軟骨炎を含む血管炎の患者さんの「お手伝い役」として活動しています。患者相談イベントでは、普段の外来診療ではお聞きできない悩みや疑問に可能な限り丁寧にお答えすることを心掛けています。一人でも多くの患者さんに寄り添い、明るい未来を一緒に切り開くための支援を続けていきたいと考えています。

■略歴

1997年 3月 京都大学医学部医学科　卒業

1997年 5月 京都大学医学部附属病院　第2内科　研修医

1998年 6月 市立岸和田市民病院　代謝内分泌内科　研修医

2000年 4月 京都大学大学院医学研究科　博士課程　

内科学講座臨床免疫学　入学

2004年 3月 同上博士課程　修了

2004年 4月 京都大学医学部附属病院　免疫・膠原病内科　医員

2006年 8月 同上　特定病院助教

2008年 6月 （米国ニューヨーク）　ファインスタイン医学研究所　

自己免疫・筋骨格疾患センター　研究員　勤務

2010年 8月 京都大学大学院医学研究科　

内科学講座臨床免疫学（免疫・膠原病内科）　助教

2014年 6月 同上　病院講師

2020年 8月 同上　講師

　　　現在 に至る

■業績

《原著，欧文》（すべて査読あり）

  1. Kawabata D, Tanaka M, Fujii T, Umehara H, Fujita Y, Yoshifuji H, Mimori T, Ozaki S. Ameliorative effects of follistatin-related protein/TSC-36/FSTL1 on joint inflammation in a mouse model of arthritis. Arthritis Rheum 2004, 50:660-668, 被引用回数76
  2. Yoshifuji H, Umehara H, Maruyama H, Itoh M, Tanaka M, Kawabata D, Fujii T, Mimori T. Amelioration of experimental arthritis by a calpain-inhibitory compound: regulation of cytokine production by E-64-d in vivo and in vitro. Int Immunol 2005, 17:1327-1336, ファーストオーサー, コレスポンディングオーサー, 学位論文, 被引用回数25
  3. Yoshifuji H, Fujii T, Kobayashi S, Imura Y, Fujita Y, Kawabata D, Usui T, Tanaka M, Nagai S, Umehara H, Mimori T. Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies. Autoimmunity 2006, 39:233-241, ファーストオーサー, コレスポンディングオーサー, 被引用回数185
  4. Murakami K, Fujii T, Yukawa N, Yoshifuji H, Kawabata D, Tanaka M, Usui T, Mimori T. Successful treatment of a patient with refractory adult Still’s disease by tacrolimus. Mod Rheumatol 2007, 17:167-170, 被引用回数16
  5. Ito Y, Kawabata D, Yukawa N, Yoshifuji H, Usui T, Tanaka M, Fujii T, Mimori T. Severe subcutaneous generalized edema in a patient with dermatomyositis. Mod Rheumatol 2007, 17:171-173, 被引用回数20
  6. Nakayamada S, Saito K, Umehara H, Ogawa N, Sumida T, Ito S, Minota S, Nara H, Kondo H, Okada J, Mimori T, Yoshifuji H, Sano H, Hashimoto N, Sugai S, Tanaka Y. Efficacy and safety of mizoribine for the treatment of Sjögren’s syndrome: a multicenter open-label clinical trial. Mod Rheumatol 2007, 17:464-469, 被引用回数35
  7. Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T, Shimizu M, Kawabata D, Yukawa N, Hashimoto M, Sakaguchi N, Sakaguchi S, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Mimori T. Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis. Arthritis Rheum 2009, 60:2294-2303, 被引用回数137
  8. Nakashima R, Imura Y, Kobayashi S, Yukawa N, Yoshifuji H, Nojima T, Kawabata D, Ohmura K, Usui T, Fujii T, Okawa K, Mimori T. The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody. Rheumatology (Oxford) 2010, 49:433-440, 被引用回数279
  9. Venkatesh J, Yoshifuji H, Kawabata D, Chinnasamy P, Stanevsky A, Grimaldi CM, Cohen-Solal J, Diamond B. Antigen is required for maturation and activation of pathogenic anti-DNA antibodies and systemic inflammation. J Immunol 2011, 186:5304-5312, セカンドオーサー, 被引用回数20
  10. Iguchi-Hashimoto M, Usui T, Yoshifuji H, Shimizu M, Kobayashi S, Ito Y, Murakami K, Shiomi A, Yukawa N, Kawabata D, Nojima T, Ohmura K, Fujii T, Mimori T. Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals. PLoS One 2011, 6:e27020, 被引用回数17
  11. Yukawa N, Fujii T, Kondo-Ishikawa S, Yoshifuji H, Kawabata D, Nojima T, Ohmura K, Usui T, Mimori T. Correlation of antinuclear antibody and anti-double-stranded DNA antibody with clinical response to infliximab in patients with rheumatoid arthritis: a retrospective clinical study. Arthritis Res Ther 2011, 13:R213, 被引用回数39
  12. Murakami K, Tanaka M, Usui T, Kawabata D, Shiomi A, Iguchi-Hashimoto M, Shimizu M, Yukawa N, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Umehara H, Mimori T. Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4. FEBS Lett 2012, 586:319-324, 被引用回数62
  13. Imura Y, Shirai Y, Nojima T, Nakashima R, Yamagata H, Miyachi K, Yoshifuji H, Kawabata D, Ohmura K, Usui T, Fujii T, Mimori T. NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA. Mod Rheumatol 2012, 22:685-694, 被引用回数2
  14. Kiyama K, Kawabata D, Hosono Y, Kitagori K, Yukawa N, Yoshifuji H, Omura K, Fujii T, Mimori T. Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance. Arthritis Res Ther 2012, 14:R86, 被引用回数67
  15. Nakano M, Fujii T, Hashimoto M, Yukawa N, Yoshifuji H, Ohmura K, Nakaizumi A, Mimori T. Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. Clin Exp Immunol 2012, 170:94-100, 被引用回数45
  16. Kitai Y, Murakami K, Yoshifuji H, Yukawa N, Kawabata D, Ohmura K, Fujii T, Mimori T. A case of Behçet’s disease developing after poststreptococcal acute glomerulonephritis. Mod Rheumatol 2013, 23:1221-1225, 被引用回数1
  17. Terao C, Hashimoto M, Yamamoto K, Murakami K, Ohmura K, Nakashima R, Yamakawa N, Yoshifuji H, Yukawa N, Kawabata D, Usui T, Yoshitomi H, Furu M, Yamada R, Matsuda F, Ito H, Fujii T, Mimori T. Three groups in the 28 joints for rheumatoid arthritis synovitis–analysis using more than 17,000 assessments in the KURAMA database. PLoS One 2013, 8:e59341, 被引用回数47
  18. Katayama M, Ohmura K, Yukawa N, Terao C, Hashimoto M, Yoshifuji H, Kawabata D, Fujii T, Iwakura Y, Mimori T. Neutrophils are essential as a source of IL-17 in the effector phase of arthritis. PLoS One 2013, 8:e62231, 被引用回数65
  19. Tsuji H, Yoshifuji H, Nakashima R, Imura Y, Yukawa N, Ohmura K, Miyagawa-Hayashino A, Kabashima K, Mimori T. Sweet’s syndrome associated with systemic lupus erythematosus: a case report and review of the literature. J Dermatol 2013, 40:641-648, セカンドオーサー, 被引用回数14
  20. Kawabata H, Kadowaki N, Nishikori M, Kitawaki T, Kondo T, Ishikawa T, Yoshifuji H, Yamakawa N, Imura Y, Mimori T, Matsumura Y, Miyachi Y, Matsubara T, Yanagita M, Haga H, Takaori-Kondo A. Clinical features and treatment of multicentric castleman’s disease: a retrospective study of 21 Japanese patients at a single institute. J Clin Exp Hematop 2013, 53:69-77, 被引用回数73
  21. Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F. Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Am J Hum Genet 2013, 93:289-297, セカンドオーサー, 被引用回数134
  22. Terao C, Yoshifuji H, Ohmura K, Murakami K, Kawabata D, Yurugi K, Tazaki J, Kinoshita H, Kimura A, Akizuki M, Kawaguchi Y, Yamanaka H, Miura Y, Maekawa T, Saji H, Mimori T, Matsuda F. Association of Takayasu arteritis with HLA-B 67:01 and two amino acids in HLA-B protein. Rheumatology (Oxford) 2013, 52:1769-1774, セカンドオーサー, 被引用回数39
  23. Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Yoshifuji H, Ohta A, Matsumoto I, Sumida T. Primary and secondary surveys on epidemiology of Sjögren’s syndrome in Japan. Mod Rheumatol 2014, 24:464-470, 被引用回数51
  24. Yamakawa N, Fujimoto M, Kawabata D, Terao C, Nishikori M, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Ohmura K, Fujii T, Kitano T, Kondo T, Yurugi K, Miura Y, Maekawa T, Saji H, Takaori-Kondo A, Matsuda F, Haga H, Mimori T. A clinical, pathological, and genetic characterization of methotrexate-associated lymphoproliferative disorders. J Rheumatol 2014, 41:293-299, 被引用回数98
  25. Tanaka K, Terao C, Ohmura K, Takahashi M, Nakashima R, Imura Y, Yoshifuji H, Yukawa N, Usui T, Fujii T, Mimori T, Matsuda F. Significant association between CYP3A5 polymorphism and blood concentration of tacrolimus in patients with connective tissue diseases. J Hum Genet 2014, 59:107-109, 被引用回数4
  26. Terao C, Hashimoto M, Furu M, Nakabo S, Ohmura K, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Matsuda F, Ito H, Fujii T, Mimori T. Inverse association between air pressure and rheumatoid arthritis synovitis. PLoS One 2014, 9:e85376, 被引用回数22
  27. Yokoyama T, Fujii T, Kondo-Ishikawa S, Yamakawa N, Nakano M, Yukawa N, Yoshifuji H, Ohmura K, Mimori T. Association between anti-U1 ribonucleoprotein antibodies and inflammatory mediators in cerebrospinal fluid of patients with neuropsychiatric systemic lupus erythematosus. Lupus 2014, 23:635-642, 被引用回数16
  28. Yamamoto N, Yamaguchi H, Ohmura K, Yokoyama T, Yoshifuji H, Yukawa N, Kawabata D, Fujii T, Morita S, Nagata S, Mimori T. Serum milk fat globule epidermal growth factor 8 elevation may subdivide systemic lupus erythematosus into two pathophysiologically distinct subsets. Lupus 2014, 23:386-394, 被引用回数18
  29. Nakajima T, Kawabata D, Nakabo S, Miyagawa-Hayashino A, Yukawa N, Yoshifuji H, Ohmura K, Fujii T, Mimori T. Successful treatment with tocilizumab in a case of intralymphatic histiocytosis associated with rheumatoid arthritis. Intern Med 2014, 53:2255-2258, 被引用回数10
  30. Shiheido H, Kitagori K, Sasaki C, Kobayashi S, Aoyama T, Urata K, Oku T, Hirayama Y, Yoshitomi H, Hikida M, Yoshifuji H, Mimori T, Watanabe T, Shimizu J. Human T cells expressing BEND3 on their surface represent a novel subpopulation that preferentially produces IL-6 and IL-8. Immun Inflamm Dis 2014, 2:35-43, 被引用回数2
  31. Ogata A, Atsumi T, Fukuda T, Hirabayashi Y, Inaba M, Ishiguro N, Kai M, Kawabata D, Kida D, Kohsaka H, Matsumura R, Minota S, Mukai M, Sumida T, Takasugi K, Tamaki S, Takeuchi T, Ueda A, Yamamoto K, Yamanaka H, Yoshifuji H, Nomura A; Musashi Study Investigators. Sustainable Efficacy of Switching From Intravenous to Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken) 2015, 67:1354-1362, 被引用回数29
  32. Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Nakaoka Y, Takahashi M, Amiya E, Tamura N, Nakajima T, Origuchi T, Horita T, Matsukura M, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F. Takayasu arteritis and ulcerative colitis: high rate of co-occurrence and genetic overlap. Arthritis Rheumatol 2015, 67:2226-2232, 被引用回数103
  33. Kiyama K, Yoshifuji H, Kandou T, Hosono Y, Kitagori K, Nakashima R, Imura Y, Yukawa N, Ohmura K, Fujii T, Kawabata D, Mimori T. Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease. BMC Musculoskelet Disord 2015, 16:129, セカンドオーサー, コレスポンディングオーサー, 被引用回数30
  34. Kono M, Miura N, Fujii T, Ohmura K, Yoshifuji H, Yukawa N, Imura Y, Nakashima R, Ikeda T, Umemura S, Miyatake T, Mimori T. Personal Authentication Analysis Using Finger-Vein Patterns in Patients with Connective Tissue Diseases–Possible Association with Vascular Disease and Seasonal Change. PLoS One 2015, 10:e0144952, 被引用回数5
  35. *Terao C, *Yoshifuji H, Nakajima T, Yukawa N, Matsuda F, Mimori T. Ustekinumab as a therapeutic option for Takayasu arteritis: from genetic findings to clinical application. Scand J Rheumatol 2016, 45:80-82, *Equally contributedファーストオーサー, 被引用回数56
  36. Hiramatsu S, Ohmura K, Tsuji H, Kawabata H, Kitano T, Sogabe A, Hashimoto M, Murakami K, Imura Y, Yukawa N, Yoshifuji H, Fujii T, Takaori-Kondo A, Mimori T. Successful treatment by rituximab in a patient with TAFRO syndrome with cardiomyopathy. Nihon Rinsho Meneki Gakkai Kaishi 2016, 39:64-71, 被引用回数31
  37. *Terao C, *Yoshifuji H, Yamano Y, Kojima H, Yurugi K, Miura Y, Maekawa T, Handa H, Ohmura K, Saji H, Mimori T, Matsuda F. Genotyping of relapsing polychondritis identified novel susceptibility HLA alleles and distinct genetic characteristics from other rheumatic diseases. Rheumatology (Oxford) 2016, 55:1686-1692, *Equally contributedファーストオーサー, 被引用回数26
  38. Tsuji H, Ohmura K, Nakashima R, Hashimoto M, Imura Y, Yukawa N, Yoshifuji H, Fujii T, Mimori T. Efficacy and Safety of Grapefruit Juice Intake Accompanying Tacrolimus Treatment in Connective Tissue Disease Patients. Intern Med 2016, 55:1547-1552, 被引用回数5
  39. Yamakawa N, Oe K, Yukawa N, Murakami K, Nakashima R, Imura Y, Yoshifuji H, Ohmura K, Miura Y, Tomosugi N, Kawabata H, Takaori-Kondo A, Mimori T. A Novel Phenotype of a Hereditary Hemochromatosis Type 4 with Ferroportin-1 Mutation, Presenting with Juvenile Cataracts. Intern Med 2016, 55:2697-2701, 被引用回数11
  40. Kitagori K, Yoshifuji H, Oku T, Sasaki C, Miyata H, Mori KP, Nakajima T, Ohmura K, Kawabata D, Yukawa N, Imura Y, Murakami K, Nakashima R, Usui T, Fujii T, Sakai K, Yanagita M, Hirayama Y, Mimori T. Cleaved Form of Osteopontin in Urine as a Clinical Marker of Lupus Nephritis. PLoS One 2016, 11:e0167141, セカンドオーサー, コレスポンディングオーサー, 学位指導論文, 被引用回数25
  41. Tsuji H, Yoshifuji H, Fujii T, Matsuo T, Nakashima R, Imura Y, Yukawa N, Ohmura K, Sumiyoshi S, Mimori T. Visceral disseminated varicella zoster virus infection after rituximab treatment for granulomatosis with polyangiitis. Mod Rheumatol 2017, 27:155-161, セカンドオーサー, コレスポンディングオーサー, 被引用回数16
  42. Mori M, Hashimoto M, Matsuo T, Fujii T, Furu M, Ito H, Yoshitomi H, Hirose J, Ito Y, Akizuki S, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Ohmura K, Mimori T. Cell-contact-dependent activation of CD4+ T cells by adhesion molecules on synovial fibroblasts. Mod Rheumatol 2017, 27:448-456, 被引用回数19
  43. Hosono Y, Nakashima R, Serada S, Murakami K, Imura Y, Yoshifuji H, Ohmura K, Naka T, Mimori T. Splicing factor proline/glutamine-rich is a novel autoantigen of dermatomyositis and associated with anti-melanoma differentiation-associated gene 5 antibody. J Autoimmun 2017, 77:116-122, 被引用回数17
  44. Hiwa R, Ohmura K, Nakabo S, Terao C, Murakami K, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Hashimoto M, Furu M, Ito H, Fujii T, Mimori T. Only rheumatoid factor-positive subset of anti-citrullinated peptide/protein antibody-negative rheumatoid arthritis may seroconvert to anti-citrullinated peptide/protein antibody-positive. Int J Rheum Dis 2017, 20:731-736, 被引用回数3
  45. Terao C, Kawaguchi T, Dieude P, Varga J, Kuwana M, Hudson M, Kawaguchi Y, Matucci-Cerinic M, Ohmura K, Riemekasten G, Kawasaki A, Airo P, Horita T, Oka A, Hachulla E, Yoshifuji H, Caramaschi P, Hunzelmann N, Baron M, Atsumi T, Hassoun P, Torii T, Takahashi M, Tabara Y, Shimizu M, Tochimoto A, Ayuzawa N, Yanagida H, Furukawa H, Tohma S, Hasegawa M, Fujimoto M, Ishikawa O, Yamamoto T, Goto D, Asano Y, Jinnin M, Endo H, Takahashi H, Takehara K, Sato S, Ihn H, Raychaudhuri S, Liao K, Gregersen P, Tsuchiya N, Riccieri V, Melchers I, Valentini G, Cauvet A, Martinez M, Mimori T, Matsuda F, Allanore Y. Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. Ann Rheum Dis 2017, 76:1150-1158, 被引用回数78
  46. Nakabo S, Hashimoto M, Ito S, Furu M, Ito H, Fujii T, Yoshifuji H, Imura Y, Nakashima R, Murakami K, Kuramoto N, Tanaka M, Satoh J, Ishigami A, Morita S, Mimori T, Ohmura K. Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies. Rheumatology (Oxford) 2017, 56:1217-1226, 被引用回数26
  47. Nakabo S, Yoshifuji H, Hashimoto M, Imura Y, Nakashima R, Murakami K, Kuramoto N, Ito S, Satoh J, Tanaka M, Fujii T, Mimori T, Ohmura K. Anti-carbamylated Protein Antibodies Are Detectable in Various Connective Tissue Diseases. J Rheumatol 2017, 44:1384-1388, セカンドオーサー, 被引用回数15
  48. Salah A, Yoshifuji H, Ito S, Kitagori K, Kiso K, Yamada N, Nakajima T, Haga H, Tsuruyama T, Miyagawa-Hayashino A. High Expression of Galectin-3 in Patients with IgG4-Related Disease: A Proteomic Approach. Patholog Res Int 2017, 2017:9312142, セカンドオーサー, 被引用回数28
  49. Kuramoto N, Ohmura K, Ikari K, Yano K, Furu M, Yamakawa N, Hashimoto M, Ito H, Fujii T, Murakami K, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Taniguchi A, Momohara S, Yamanaka H, Matsuda F, Mimori T, Terao C. Anti-centromere antibody exhibits specific distribution levels among anti-nuclear antibodies and may characterize a distinct subset in rheumatoid arthritis. Sci Rep 2017, 7:6911, 被引用回数9
  50. Nakajima T, Yoshifuji H, Shimizu M, Kitagori K, Murakami K, Nakashima R, Imura Y, Tanaka M, Ohmura K, Matsuda F, Terao C, Mimori T. A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production. Arthritis Res Ther 2017, 19:197, セカンドオーサー, コレスポンディングオーサー, 学位指導論文, 被引用回数26
  51. Kiso K, Yoshifuji H, Oku T, Hikida M, Kitagori K, Hirayama Y, Nakajima T, Haga H, Tsuruyama T, Miyagawa-Hayashino A. Transgelin-2 is upregulated on activated B-cells and expressed in hyperplastic follicles in lupus erythematosus patients. PLoS One 2017, 12:e0184738, セカンドオーサー, 被引用回数10
  52. Imura Y, Yukawa N, Handa T, Nakashima R, Murakami K, Yoshifuji H, Ohmura K, Ishii H, Nakata K, Mimori T. Two cases of autoimmune and secondary pulmonary alveolar proteinosis during immunosuppressive therapy in dermatomyositis with interstitial lung disease. Mod Rheumatol 2018, 28:724-729, 被引用回数7
  53. Okabe N, Ohmura K, Katayama M, Akizuki S, Carpino N, Murakami K, Nakashima R, Hashimoto M, Imura Y, Yoshifuji H, Tanaka M, Mimori T. Suppressor of TCR signaling-2 (STS-2) suppresses arthritis development in mice. Mod Rheumatol 2018, 28:626-636, 被引用回数6
  54. Notohara K, Kamisawa T, Uchida K, Zen Y, Kawano M, Kasashima S, Sato Y, Shiokawa M, Uehara T, Yoshifuji H, Hayashi H, Inoue K, Iwasaki K, Kawano H, Matsubayashi H, Moritani Y, Murakawa K, Oka Y, Tateno M, Okazaki K, Chiba T. Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey. J Gastroenterol 2018, 53:845-853, 被引用回数36
  55. Handa T, Matsui S, Yoshifuji H, Kodama Y, Yamamoto H, Minamoto S, Waseda Y, Sato Y, Kubo K, Mimori T, Chiba T, Hirai T, Mishima M. Serum soluble interleukin-2 receptor as a biomarker in immunoglobulin G4-related disease. Mod Rheumatol 2018, 28:838-844, 被引用回数27
  56. Miyagawa-Hayashino A, Yoshifuji H, Kitagori K, Ito S, Oku T, Hirayama Y, Salah A, Nakajima T, Kiso K, Yamada N, Haga H, Tsuruyama T. Increase of MZB1 in B cells in systemic lupus erythematosus: proteomic analysis of biopsied lymph nodes. Arthritis Res Ther 2018, 20:13, セカンドオーサー, 被引用回数30
  57. Iguchi T, Takaori K, Mii A, Sato Y, Suzuki Y, Yoshifuji H, Seno H, Ogawa O, Omori K, Bessho K, Kondo S, Yoshizaki T, Nakashima H, Saito T, Mimori T, Haga H, Kawano M, Yanagita M. Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease. Mod Pathol 2018, 31:890-899, 被引用回数10
  58. Takeuchi Y, Hashimoto M, Nakashima R, Tanaka M, Kuramoto N, Murakami K, Yoshifuji H, Ohmura K, Mimori T. Anti-EJ, anti-MDA5 double-positive chronic clinically amyopathic dermatomyositis: a case report. Rheumatol Adv Pract 2018, 2:rky022, 被引用回数9
  59. Shirakashi M, Yoshifuji H, Kodama Y, Chiba T, Yamamoto M, Takahashi H, Uchida K, Okazaki K, Ito T, Kawa S, Yamada K, Kawano M, Hirata S, Tanaka Y, Moriyama M, Nakamura S, Kamisawa T, Matsui S, Tsuboi H, Sumida T, Shibata M, Goto H, Sato Y, Yoshino T, Mimori T. Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study. Sci Rep 2018, 8:10262, セカンドオーサー, コレスポンディングオーサー, 被引用回数43
  60. Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A, Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F. Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. Proc Natl Acad Sci U S A 2018, 115:13045-13050, セカンドオーサー, 被引用回数60
  61. Nakayama Y, Yoshifuji H, Mori M, Kuramoto N, Murakami K, Nakashima R, Imura Y, Ohmura K, Handa T, Miyagawa-Hayashino A, Yokoi H, Mimori T. A concomitant case of pathologically proven IgG4-related disease and ANCA-associated vasculitis: case report. Mod Rheumatol Case Rep 2018, 2:84-91, セカンドオーサー, コレスポンディングオーサー, 被引用回数2
  62. Nakamura Y, Ohmura K, Dainichi T, Kuramoto N, Nakakubo Y, Takeuchi Y, Akizuki S, Murakami K, Nakashima R, Yoshifuji H, Nishie W, Izumi K, Shimizu H, Hashimoto M, Tanaka M, Sakurai T, Kitoh A, Mimori T. Simultaneous development of cutaneous vasculitis and an autoimmune bullous skin disease during anti-TNF therapy for rheumatoid arthritis: a case report and review of the literature. Mod Rheumatol Case Rep 2018, 2:130-136, 被引用回数0
  63. Iwasaki T, Nakamura Y, Nakayama S, Koita N, Maki T, Iemura Y, Haga H, Okada T, Akizuki S, Kuramoto N, Murakami K, Nakashima R, Yoshifuji H, Mimori T, Ohmura K. TAFRO syndrome complicated with occlusion of multiple cerebral arteries. Mod Rheumatol Case Rep 2018, 2:214-220, 被引用回数1
  64. Kitagori K, Yoshifuji H, Oku T, Ayaki T, Kuzuya A, Nakajima T, Akizuki S, Nakashima R, Murakami K, Ohmura K, Hirayama Y, Takahashi R, Mimori T. Utility of osteopontin in cerebrospinal fluid as a diagnostic marker for neuropsychiatric systemic lupus erythematosus. Lupus 2019, 28:414-422, セカンドオーサー, コレスポンディングオーサー, 被引用回数17
  65. Matsuo T, Hashimoto M, Sakaguchi S, Sakaguchi N, Ito Y, Hikida M, Tsuruyama T, Sakai K, Yokoi H, Shirakashi M, Tanaka M, Ito H, Yoshifuji H, Ohmura K, Fujii T, Mimori T. Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation. J Immunol 2019, 202:3161-3172, 被引用回数16
  66. Shirakashi M, Yukawa N, Sakaguchi M, Murakami K, Fujimura T, Yamakawa N, Hashimoto M, Yoshifuji H, Kawabata D, Sumiyoshi S, Yoshizawa A, Ohmura K, Haga H, Mimori T. Rosai-Dorfman disease with aortic involvement in a 58-year-old man: a case report. Mod Rheumatol Case Rep 2019, 3:160-164, 被引用回数0
  67. Yaku A, Murakami K, Mukoyama H, Shibuya S, Nakashima R, Hashimoto M, Yoshifuji H, Ohmura K, Haga H, Mimori T. Long QT syndrome caused by adrenal insufficiency secondary to IgG4-related hypophysitis: a case report and review of the literature. Mod Rheumatol Case Rep 2019, 3:150-159, 被引用回数2
  68. Nakabo S, Ohmura K, Akizuki S, Murakami K, Nakashima R, Hashimoto M, Yoshifuji H, Tanaka M, Mimori T. Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis. Mod Rheumatol 2020, 30:345-349, 被引用回数15
  69. Ishigooka N, Fujii T, Abe H, Murakami K, Nakashima R, Hashimoto M, Yoshifuji H, Tanaka M, Ito H, Ohmura K, Morita S, Mimori T. Predicting factors for disappearance of anti-mutated citrullinated vimentin antibodies in sera of patients with rheumatoid arthritis. Mod Rheumatol 2020, 30:450-457, 被引用回数2
  70. Tsuji H, Nakashima R, Hosono Y, Imura Y, Yagita M, Yoshifuji H, Hirata S, Nojima T, Sugiyama E, Hatta K, Taguchi Y, Katayama M, Tanizawa K, Handa T, Uozumi R, Akizuki S, Murakami K, Hashimoto M, Tanaka M, Ohmura K, Mimori T. Multicenter Prospective Study of the Efficacy and Safety of Combined Immunosuppressive Therapy With High-Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Diseases Accompanied by Anti-Melanoma Differentiation-Associated Gene 5-Positive Dermatomyositis. Arthritis Rheumatol 2020, 72:488-498, 被引用回数223
  71. Nakaoka Y, Isobe M, Tanaka Y, Ishii T, Ooka S, Niiro H, Tamura N, Banno S, Yoshifuji H, Sakata Y, Kawakami A, Atsumi T, Furuta S, Kohsaka H, Suzuki K, Hara R, Maejima Y, Tsukamoto H, Takasaki Y, Yamashita K, Okada N, Yamakido S, Takei S, Yokota S, Nishimoto N. Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study. Rheumatology (Oxford) 2020, 59:2427-2434, 被引用回数85
  72. Murakami I, Murakami K, Hashimoto M, Tanaka M, Ito H, Fujii T, Torii M, Ikeda K, Kuwabara A, Tanaka K, Yoshida A, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, Usui T, Morita S, Mimori T. Intake frequency of vegetables or seafoods negatively correlates with disease activity of rheumatoid arthritis. PLoS One 2020, 15:e0228852, 被引用回数9
  73. Sugihara T, Hasegawa H, Uchida HA, Yoshifuji H, Watanabe Y, Amiya E, Maejima Y, Konishi M, Murakawa Y, Ogawa N, Furuta S, Katsumata Y, Komagata Y, Naniwa T, Okazaki T, Tanaka Y, Takeuchi T, Nakaoka Y, Arimura Y, Harigai M, Isobe M; Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS). Associated factors of poor treatment outcomes in patients with giant cell arteritis: clinical implication of large vessel lesions. Arthritis Res Ther 2020, 22:72, 被引用回数40
  74. Shirakashi M, Nakashima R, Tsuji H, Tanizawa K, Handa T, Hosono Y, Akizuki S, Murakami K, Hashimoto M, Yoshifuji H, Ohmura K, Mimori T. Efficacy of plasma exchange in anti-MDA5-positive dermatomyositis with interstitial lung disease. Rheumatology (Oxford) 2020, 59:3284-3292, 被引用回数90
  75. Korogi Y, Tanaka N, Yoshifuji H, Tazaki J, Kubo T, Tanizawa K. Complete occlusion of right pulmonary artery in Behçet disease. Respirol Case Rep 2020, 8:e00594, 被引用回数1
  76. Kondo-Ishikawa S, Fujii T, Ishigooka N, Murakami K, Nakashima R, Hashimoto M, Yoshifuji H, Tanaka M, Ohmura K, Mimori T. Association of anti-NR2 and U1RNP antibodies with neurotoxic inflammatory mediators in cerebrospinal fluid from patients with neuropsychiatric systemic lupus erythematosus. Lupus 2020, 29:1673-1682, 被引用回数3
  77. Iwasaki T, Nakabo S, Terao C, Murakami K, Nakashima R, Hashimoto M, Imura Y, Yukawa N, Yoshifuji H, Miura Y, Yurugi K, Maekawa T, van Delft MAM, Trouw LA, Fujii T, Mimori T, Ohmura K. Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency. Arthritis Res Ther 2020, 22:248, 被引用回数2
  78. Niwamoto T, Handa T, Matsui S, Yamamoto H, Yoshifuji H, Abe H, Matsumoto H, Kodama Y, Chiba T, Seno H, Mimori T, Hirai T. Phenotyping of IgG4-related diseases based on affected organ pattern: A multicenter cohort study using cluster analysis. Mod Rheumatol 2021, 31:235-240, 被引用回数10
  79. Gon Y, Yoshifuji H, Nakajima T, Murakami K, Nakashima R, Ohmura K, Mimori T, Terao C. Long-term outcomes of refractory Takayasu arteritis patients treated with biologics including ustekinumab. Mod Rheumatol 2021, 31:678-683, セカンドオーサー, コレスポンディングオーサー, 被引用回数21
  80. Tsuji H, Yoshifuji H, Shindo T, Hishizawa M, Ishida A, Fujimoto M, Kitagori K, Akizuki S, Murakami K, Nakashima R, Hashimoto M, Tanaka M, Ohmura K. Primary hepatic lymphoma as other iatrogenic immunodeficiency-related lymphoproliferative disorders: a case report and review of the literature. Mod Rheumatol Case Rep 2021, 5:172-177, セカンドオーサー, コレスポンディングオーサー, 被引用回数4
  81. Yoshifuji H, Kagebayashi S, Kinoshita H, Fujii T, Okano Y, Katsushima M, Mimori T. A case of pulmonary arterial hypertension complicated by anti-neutrophil cytoplasmic antibody-associated vasculitis and systemic sclerosis. Immunol Med 2021, 44:263-269, ファーストオーサー, コレスポンディングオーサー, 被引用回数0
  82. Doi H, Ohmura K, Tabuchi Y, Hashimoto M, Takase Y, Inaba R, Kozuki T, Iwasaki T, Taniguchi M, Kitagori K, Akizuki S, Murakami K, Nakashima R, Yoshifuji H, Yamamoto W, Tanaka M, Akio M. Validation and verification of the Japanese version of the systemic lupus erythematosus symptom checklist for patient quality of life. Lupus 2021, 30:1108-1115, 被引用回数6
  83. Ota M, Nagafuchi Y, Hatano H, Ishigaki K, Terao C, Takeshima Y, Yanaoka H, Kobayashi S, Okubo M, Shirai H, Sugimori Y, Maeda J, Nakano M, Yamada S, Yoshida R, Tsuchiya H, Tsuchida Y, Akizuki S, Yoshifuji H, Ohmura K, Mimori T, Yoshida K, Kurosaka D, Okada M, Setoguchi K, Kaneko H, Ban N, Yabuki N, Matsuki K, Mutoh H, Oyama S, Okazaki M, Tsunoda H, Iwasaki Y, Sumitomo S, Shoda H, Kochi Y, Okada Y, Yamamoto K, Okamura T, Fujio K. Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases. Cell 2021, 184:3006-3021.e17, 被引用回数132
  84. Takase Y, Iwasaki T, Doi H, Tsuji H, Hashimoto M, Ueno K, Inaba R, Kozuki T, Taniguchi M, Tabuchi Y, Watanabe R, Kitagori K, Akizuki S, Murakami K, Nakashima R, Yoshifuji H, Itaya T, Yamamoto W, Uozumi R, Tanaka M, Ohmura K, Morinobu A. Correlation between irreversible organ damage and the quality of life of patients with systemic lupus erythematosus: The Kyoto Lupus Cohort survey. Lupus 2021, 30:1577-1585, 被引用回数9
  85. Kadoba K, Watanabe R, Iwasaki T, Nakajima T, Kitagori K, Akizuki S, Murakami K, Nakashima R, Hashimoto M, Tanaka M, Ohmura K, Morinobu A, Terao C, Yoshifuji H. A susceptibility locus in the IL12B but not LILRA3 region is associated with vascular damage in Takayasu arteritis. Sci Rep 2021, 11:13667, ラストオーサー, 被引用回数13
  86. Shima A, Maki T, Mimura N, Yamashita H, Emoto N, Yoshifuji H, Takahashi R. A case of reversible cerebral vasoconstriction syndrome associated with anti-phospholipid antibody syndrome and systemic lupus erythematosus. eNeurologicalSci 2021, 24:100351, 被引用回数9
  87. Takimoto-Ito R, Kambe N, Kogame T, Otsuka A, Nomura T, Izawa K, Tabuchi Y, Yoshifuji H, Takeuchi Y, Kabashima K. Refractory serum immunoglobulin M elevation during anti-interleukin (IL)-1- or IL-6-targeted treatment in four patients with Schnitzler syndrome. J Dermatol 2021, 48:1789-1792, 被引用回数6
  88. Mukoyama H, Shirakashi M, Tanaka N, Iwasaki T, Nakajima T, Onizawa H, Tsuji H, Kitagori K, Akizuki S, Nakashima R, Murakami K, Tanaka M, Morinobu A, Yoshifuji H. The clinical features of pulmonary artery involvement in Takayasu arteritis and its relationship with ischemic heart diseases and infection. Arthritis Res Ther 2021, 23:293, ラストオーサー, コレスポンディングオーサー, 被引用回数11
  89. Ma S, Murakami K, Saito R, Ito H, Murata K, Nishitani K, Hashimoto M, Tanaka M, Taniguchi M, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, Morinobu A, Mimori T. Increased Ratio of CD14++CD80+ Cells/CD14++CD163+ Cells in the Infrapatellar Fat Pad of End-Stage Arthropathy Patients. Front Immunol 2021, 12:774177, 被引用回数2
  90. Rose E, Ferrada MA, Quinn KA, Goodspeed W, Arnaud L, Sharma A, Yoshifuji H, Kim J, Allen C, Sirajuddin A, Chen M, Grayson PC. Physician Global Assessment as a Disease Activity Measure for Relapsing Polychondritis. Arthritis Care Res (Hoboken) 2022, 74:1269-1276, 被引用回数5
  91. Nakajima T, Watanabe R, Hashimoto M, Murata K, Murakami K, Tanaka M, Ito H, Yamamoto W, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, Matsuda S, Morinobu A. Neutrophil count reduction 1 month after initiating tocilizumab can predict clinical remission within 1 year in rheumatoid arthritis patients. Rheumatol Int 2022, 42:1983-1991, 被引用回数5
  92. Shirakashi M, Maruya M, Hirota K, Tsuruyama T, Matsuo T, Watanabe R, Murata K, Tanaka M, Ito H, Yoshifuji H, Ohmura K, Elewaut D, Sakaguchi S, Fagarasan S, Mimori T, Hashimoto M. Effect of Impaired T Cell Receptor Signaling on the Gut Microbiota in a Mouse Model of Systemic Autoimmunity. Arthritis Rheumatol 2022, 74:641-653, 被引用回数24
  93. Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M. Establishing clinical remission criteria and the framework of a treat-to-target algorithm for Takayasu arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour and Welfare for intractable vasculitis. Mod Rheumatol 2022, 32:930-937, 被引用回数7
  94. Iwasaki T, Doi H, Tsuji H, Tabuchi Y, Hashimoto M, Kitagori K, Akizuki S, Murakami K, Nakashima R, Yoshifuji H, Yamamoto W, Tanaka M, Ohmura K, Morinobu A. Phenotypic landscape of systemic lupus erythematosus: An analysis of the Kyoto Lupus Cohort. Mod Rheumatol 2022, 32:571-576, 被引用回数4
  95. Ma S, Murakami K, Tanaka K, Hashimoto M, Tanaka M, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, Morinobu A, Mimori T. Fatostatin ameliorates inflammation without affecting cell viability. FEBS Open Bio 2022, 12:594-604, 被引用回数1
  96. Matsuo T, Sasai T, Nakashima R, Kuwabara Y, Kato ET, Murakami I, Onizawa H, Akizuki S, Murakami K, Hashimoto M, Yoshifuji H, Tanaka M, Morinobu A, Mimori T. ECG Changes Through Immunosuppressive Therapy Indicate Cardiac Abnormality in Anti-MDA5 Antibody-Positive Clinically Amyopathic Dermatomyositis. Front Immunol 2022, 12:765140, 被引用回数8
  97. Tsuji H, Kuramoto N, Sasai T, Shirakashi M, Onizawa H, Kitagori K, Akizuki S, Nakashima R, Watanabe R, Onishi A, Murakami K, Yoshifuji H, Tanaka M, Hashimoto M, Ohmura K, Morinobu A. Autoantibody profiles associated with morbidity and mortality in scleroderma renal crisis. Rheumatology (Oxford) 2022, 61:4130-4135, 被引用回数6
  98. Yamamoto M, Nojima M, Kamekura R, Kuribara-Souta A, Uehara M, Yamazaki H, Yoshikawa N, Aochi S, Mizushima I, Watanabe T, Nishiwaki A, Komai T, Shoda H, Kitagori K, Yoshifuji H, Hamano H, Kawano M, Takano KI, Fujio K, Tanaka H. The differential diagnosis of IgG4-related disease based on machine learning. Arthritis Res Ther 2022, 24:71, 被引用回数2
  99. Fukui A, Nakayama Y, Yoshida T, Murakami K, Kadoba K, Onizawa H, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, Sugimoto A, Yamamoto S, Morinobu A. A case of intestinal amoebiasis mimicking intestinal Behçet’s disease. Mod Rheumatol Case Rep 2022, 6:270-272, 被引用回数1
  100. Nakajima T, Yoshifuji H, Yamano Y, Yurugi K, Miura Y, Maekawa T, Yoshida T, Handa H, Ohmura K, Mimori T, Terao C. Co-occurrence of relapsing polychondritis and autoimmune thyroid diseases. Orphanet J Rare Dis 2022, 17:101, セカンドオーサー, 被引用回数1
  101. Yoshida T, Yoshifuji H, Shirakashi M, Nakakura A, Murakami K, Kitagori K, Akizuki S, Nakashima R, Ohmura K, Morinobu A. Risk factors for the recurrence of relapsing polychondritis. Arthritis Res Ther 2022, 24:127, セカンドオーサー, コレスポンディングオーサー, 被引用回数5
  102. Tabuchi Y, Katsushima M, Nishida Y, Shirakashi M, Tsuji H, Onizawa H, Kitagori K, Akizuki S, Nakashima R, Murakami K, Murata K, Yoshifuji H, Tanaka M, Morinobu A, Hashimoto M. Oral dextran sulfate sodium administration induces peripheral spondyloarthritis features in SKG mice accompanied by intestinal bacterial translocation and systemic Th1 and Th17 cell activation. Arthritis Res Ther 2022, 24:176, 被引用回数1
  103. Yoshida T, Tsuji H, Onishi A, Takase Y, Shirakashi M, Onizawa H, Hiwa R, Kitagori K, Akizuki S, Nakashima R, Tanaka M, Yoshifuji H, Morinobu A. Medium-term impact of the SARS-CoV-2 mRNA vaccine against disease activity in patients with systemic lupus erythematosus. Lupus Sci Med 2022, 9:e000727, 被引用回数8
  104. Mitani K, Funaki T, Tanji M, Onizawa H, Yoshifuji H, Fushimi Y, Torimaki S, Yoshida K, Miyamoto S. Detecting immunoglobulin G4-related intracranial arteriopathy with magnetic resonance vessel wall imaging: a preliminary experience in two cases. BMC Neurol 2022, 22:476, 被引用回数0
  105. Yamaguchi E, Kadoba K, Watanabe R, Iwasaki T, Kitagori K, Akizuki S, Murakami K, Nakashima R, Hashimoto M, Tanaka M, Morinobu A, Yoshifuji H. Clinical profile and outcome of large-vessel giant cell arteritis in Japanese patients: A single-centre retrospective cohort study. Mod Rheumatol 2023, 33:175-181, ラストオーサー, 被引用回数8
  106. Sasai T, Nakashima R, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A. A new autoantibody to valyl transfer RNA synthetase associated with anti-synthetase syndrome. Rheumatology (Oxford) 2023, 62:e155-e157, 被引用回数6
  107. Sugihara T, Uchida HA, Yoshifuji H, Maejima Y, Naniwa T, Katsumata Y, Okazaki T, Ishizaki J, Murakawa Y, Ogawa N, Dobashi H, Horita T, Tanaka Y, Furuta S, Takeuchi T, Komagata Y, Nakaoka Y, Harigai M. Association between the patterns of large-vessel lesions and treatment outcomes in patients with large-vessel giant cell arteritis. Mod Rheumatol 2023, 33:1145-1153, 被引用回数2
  108. Takimoto-Ito R, Kambe N, Kogame T, Nomura T, Izawa K, Jo T, Kazuma Y, Yoshifuji H, Tabuchi Y, Abe H, Yamamoto M, Nakajima K, Tomita O, Yagi Y, Katagiri K, Matsuzaka Y, Takeuchi Y, Hatanaka M, Kanekura T, Takeuchi S, Kadono T, Fujita Y, Migita K, Fujino T, Akagi T, Mukai T, Nagano T, Kawano M, Kimura H, Okubo Y, Morita A, Hide M, Satoh T, Asahina A, Kanazawa N, Kabashima K. Summary of the current status of clinically diagnosed cases of Schnitzler syndrome in Japan. Allergol Int 2023, 72:297-305, 被引用回数5
  109. Takase Y, Shirakashi M, Nishida Y, Katsushima M, Onizawa H, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Onishi A, Nakashima R, Murakami K, Yoshifuji H, Tanaka M, Tsuruyama T, Morinobu A, Hashimoto M. Enteric Toll-like receptor 7 stimulation causes acute exacerbation in lupus-susceptible mice. Clin Rheumatol 2023, 42:1185-1194, 被引用回数0
  110. Zhang S, Tsuji H, Jin H, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Tanaka M, Arase H, Ohmura K, Morinobu A. Rheumatoid factor recognizes specific domains of the IgG heavy chain complexed with HLA class II molecules. Rheumatology (Oxford) 2023, 62:3151-3155, 被引用回数1
  111. Nakajima T, Doi H, Watanabe R, Murata K, Takase Y, Inaba R, Itaya T, Iwasaki T, Shirakashi M, Tsuji H, Kitagori K, Akizuki S, Nakashima R, Onishi A, Yoshifuji H, Tanaka M, Ito H, Hashimoto M, Ohmura K, Morinobu A. Factors associated with osteoporosis and fractures in patients with systemic lupus erythematosus: Kyoto Lupus Cohort. Mod Rheumatol 2023, 34:113-121, 被引用回数3
  112. Gon Y, Kandou T, Tsuruyama T, Iwasaki T, Kitagori K, Murakami K, Nakashima R, Akizuki S, Morinobu A, Hikida M, Mimori T, Yoshifuji H. Increased number of T cells and exacerbated inflammatory pathophysiology in a human IgG4 knock-in MRL/lpr mouse model. PLoS One 2023, 18:e0279389, ラストオーサー, コレスポンディングオーサー, 学位指導論文, 被引用回数1
  113. Onishi A, Tsuji H, Takase Y, Nakakubo Y, Iwasaki T, Kozuki T, Yoshida T, Shirakashi M, Onizawa H, Hiwa R, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Tanaka M, Morinobu A. Comparisons of SLE-DAS and SLEDAI-2K and classification of disease activity based on the SLE-DAS with reference to patient-reported outcomes. Rheumatology (Oxford) 2023, 62:3909-3915, 被引用回数5
  114. Kitagori K, Oku T, Wakabayashi M, Nakajima T, Nakashima R, Murakami K, Hirayama Y, Ishihama Y, Ohmura K, Morinobu A, Mimori T, Yoshifuji H. Expression of S100A8 protein on B cells is associated with disease activity in patients with systemic lupus erythematosus. Arthritis Res Ther 2023, 25:76, ラストオーサー, コレスポンディングオーサー, 被引用回数4
  115. Nakayama Y, Nakashima R, Handa T, Ohsumi A, Yamada Y, Nakajima D, Yutaka Y, Tanaka S, Hamada S, Ikezoe K, Tanizawa K, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Yoshifuji H, Date H, Morinobu A. Prognosis of patients with systemic sclerosis-related interstitial lung disease on the lung transplant waiting list: a retrospective study. Sci Rep 2023, 13:10150, 被引用回数2
  116. Sasai T, Nakashima R, Tsuji H, Nakajima T, Imura Y, Yoshida Y, Hirata S, Shirakashi M, Hiwa R, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A. Long-Term Prognosis of Antimelanoma Differentiation-Associated Gene 5-Positive Dermatomyositis With Interstitial Lung Disease. J Rheumatol 2023, 50:1454-1461, 被引用回数3
  117. Mukoyama H, Murakami K, Onizawa H, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Nakashima R, Onishi A, Yoshifuji H, Tanaka M, Morinobu A. A case of atypical IgG4-related disease presenting hypereosinophilia, polyneuropathy, and liver dysfunction. Mod Rheumatol Case Rep 2023, 8:172-177, 被引用回数0
  118. Okuma K, Oku T, Sasaki C, Kitagori K, Mimori T, Aramori I, Hirayama Y, Yoshifuji H. Similarity and difference between systemic lupus erythematosus and NZB/W F1 mice by multi-omics analysis. Mod Rheumatol 2024, 34:359-368, ラストオーサー, コレスポンディングオーサー, 学位指導論文, 被引用回数1
  119. Sugihara T, Yoshifuji H, Uchida HA, Maejima Y, Watanabe Y, Tanemoto K, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Niiro H, Ishii T, Nakaoka Y, Harigai M. Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis. Mod Rheumatol 2024, 34:568-575, セカンドオーサー, 被引用回数1
  120. Nishida Y, Shirakashi M, Hashii N, Nakashima R, Nakayama Y, Katsushima M, Watanabe R, Onizawa H, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Onishi A, Murakami K, Yoshifuji H, Tanaka M, Tsuruyama T, Morinobu A, Hashimoto M. Pathogenicity of IgG-Fc desialylation and its association with Th17 cells in an animal model of systemic lupus erythematosus. Mod Rheumatol 2024, 34:523-529, 被引用回数1
  121. Nakaizumi H, Kambe N, Irie H, Kaku Y, Fujimoto M, Yoshifuji H, Kazuma Y, Katagiri K, Kanekura T, Kabashima K. Neutrophilic epitheliotropism, proposed as an auto-inflammatory condition of neutrophilic urticarial dermatosis including Schnitzler syndrome, is also observed in Japanese cases. J Dermatol 2024, 51:592-596, 被引用回数0
  122. Yoshifuji H, Nakaoka Y, Uchida HA, Sugihara T, Watanabe Y, Funakoshi S, Isobe M, Harigai M; Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS). Organ Damage and Quality of Life in Takayasu Arteritis – Evidence From a National Registry Analysis. Circ J 2024, 88:285-294, ファーストオーサー, コレスポンディングオーサー, 被引用回数2
  123. Ishikawa Y, Tanaka N, Asano Y, Kodera M, Shirai Y, Akahoshi M, Hasegawa M, Matsushita T, Saito K, Motegi SI, Yoshifuji H, Yoshizaki A, Kohmoto T, Takagi K, Oka A, Kanda M, Tanaka Y, Ito Y, Nakano K, Kasamatsu H, Utsunomiya A, Sekiguchi A, Niiro H, Jinnin M, Makino K, Makino T, Ihn H, Yamamoto M, Suzuki C, Takahashi H, Nishida E, Morita A, Yamamoto T, Fujimoto M, Kondo Y, Goto D, Sumida T, Ayuzawa N, Yanagida H, Horita T, Atsumi T, Endo H, Shima Y, Kumanogoh A, Hirata J, Otomo N, Suetsugu H, Koike Y, Tomizuka K, Yoshino S, Liu X, Ito S, Hikino K, Suzuki A, Momozawa Y, Ikegawa S, Tanaka Y, Ishikawa O, Takehara K, Torii T, Sato S, Okada Y, Mimori T, Matsuda F, Matsuda K, Amariuta T, Imoto I, Matsuo K, Kuwana M, Kawaguchi Y, Ohmura K, Terao C. GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region. Nat Commun 2024, 15:319, 被引用回数4
  124. Shirakashi M, Nishida Y, Nakashima R, Fujimoto M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Morinobu A, Yoshifuji H. TAFRO syndrome is associated with anti-SSA/Ro60 antibodies, in contrast to idiopathic Castleman disease. Sci Rep 2024, 14:2889, ラストオーサー, コレスポンディングオーサー, 被引用回数3
  125. Sasai T, Ishikawa Y, Nakashima R, Isayama T, Tanizawa K, Handa T, Shirakashi M, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Yoshifuji H, Mimori T, Morinobu A. Anti-aminoacyl tRNA synthetase antibodies showing the discrepancy between enzyme-linked immunosorbent assay and RNA-immunoprecipitation. Immunol Med 2024, 47:166-175, 被引用回数0
  126. Mizushima I, Morikage N, Ito E, Kasashima F, Matsumoto Y, Sawa N, Yoshifuji H, Saeki T, Shintani-Domoto Y, Shimada S, Takayama T, Amiya E, Ozawa M, Takahashi M, Fujinaga Y, Katsumata T, Obitsu Y, Izawa A, Kanno H, Oyama-Manabe N, Ishizaka N, Nagasawa T, Takahashi H, Ohki T, Kawano M, Kasashima S; Joint Working Group from the Japanese Circulation Society and the Ministry of Health, Labour and Welfare Study Group. Validation of the Diagnostic Criteria for IgG4-Related Periaortitis/Periarteritis and Retroperitoneal Fibrosis (IgG4PA/RPF) 2018, and Proposal of a Revised 2023 Version for IgG4-Related Cardiovascular/Retroperitoneal Disease. Circ J 2024, 88:1679-1688, 被引用回数1
  127. Fujino M, Kawashima M, Yoshifuji H, Nakashima R, Yamada Y, Matsumoto Y, Kawaguchi-Sakita N, Mori Y, Pu F, Yamaguchi A, Kawaguchi K, Takada M, Toi M. Remarkable remission of symptomatic dermatomyositis after curative breast cancer surgery. Int Cancer Conf J 2024, 13:111-118, 被引用回数0
  128. Taniguchi T, Hiwa R, Shoji M, Yamaguchi E, Shirakashi M, Onizawa H, Tsuji H, Kitagori K, Nakashima R, Akizuki S, Onishi A, Yoshifuji H, Tanaka M, Morinobu A. Avacopan’s potential to decrease MPO-ANCA titres concurrent with ameliorated activity in ANCA-associated vasculitis. Mod Rheumatol Case Rep 2024, 8:314-317, 被引用回数0
  129. Manabe A, Kadoba K, Hiwa R, Kotani T, Shoji M, Shirakashi M, Tsuji H, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Yamamoto W, Okazaki A, Matsuda S, Gon T, Watanabe R, Hashimoto M, Morinobu A. Risk factors for serious infections and infection-related mortality in patients with microscopic polyangiitis: Multicentre REVEAL cohort study. Mod Rheumatol 2024, 34:1185-1193, 被引用回数1
  130. Futatsusako H, Hashimoto R, Yamamoto M, Ito J, Matsumura Y, Yoshifuji H, Shirakawa K, Takaori-Kondo A; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sato K, Nagao M, Takayama K. Longitudinal analysis of genomic mutations in SARS-CoV-2 isolates from persistent COVID-19 patient. iScience 2024, 27:109597, 被引用回数0
  131. Ishikawa Y, Yoshida H, Yoshifuji H, Ohmura K, Origuchi T, Ishii T, Mimori T, Morinobu A, Shiokawa M, Terao C. Anti-integrin αvβ6 antibody in Takayasu arteritis patients with or without ulcerative colitis. Front Immunol 2024, 15:1387516, 被引用回数0
  132. Naito R, Hiwa R, Inaba R, Murakami K, Kitoh A, Kaku Y, Murata T, Ichimura Y, Okiyama N, Nishino I, Shirakashi M, Onizawa H, Tsuji H, Kitagori K, Akizuki S, Nakashima R, Onishi A, Tanaka M, Yoshifuji H, Morinobu A. A Case of Vesiculobullous Dermatomyositis with Anti-NXP-2 Antibody without Malignancy. Mod Rheumatol Case Rep 2024, 2024 Aug 1:rxae037, 被引用回数0
  133. Miyamae T, Manabe Y, Sugihara T, Umezawa N, Yoshifuji H, Tamura N, Abe Y, Furuta S, Nagafuchi H, Ishizaki J, Nakano N, Atsumi T, Karino K, Amano K, Kurasawa T, Ito S, Yoshimi R, Ogawa N, Banno S, Naniwa T, Ito S, Hara A, Hirahara S, Uchida HA, Onishi Y, Murakawa Y, Komagata Y, Nakaoka Y, Harigai M. Pregnancy and childbirth in Takayasu arteritis in Japan: A nationwide retrospective study. Mod Rheumatol 2024, 2024 Aug 8:roae068, 被引用回数0
  134. Tsuji H, Nakashima R, Yasumi T, Sasai T, Ichimura Y, Shirakashi M, Onizawa H, Hiwa R, Kitagori K, Akizuki S, Onishi A, Yoshifuji H, Tanaka M, Okiyama N, Mimori T, Morinobu A. Differences in the autoantibody phenotypes and long-term outcomes between juvenile- and adult-idiopathic inflammatory myopathies. Semin Arthritis Rheum 2024, 68:152530, 被引用回数0
  135. Katsushima M, Nakayama Y, Yoshida T, Nishida Y, Shirakashi M, Nakashima R, Yoshifuji H, Ito S, Satoh J, Yamamoto M, Watanabe R, Emori T, Kamiya T, Nitahara Y, Nakagama Y, Ohtani N, Kido Y, Morinobu A, Hashimoto M. Association of gut commensal translocation with autoantibody production in systemic lupus erythematosus. Rheumatology (Oxford) 2024, 2024 Sep 9:keae476, 被引用回数0
  136. Uchida HA, Nakaoka Y, Sugihara T, Yoshifuji H, Maejima Y, Watanabe Y, Nagafuchi H, Okazaki T, Komagata Y, Tanaka Y, Amiya E, Atsumi T, Tanemoto K, Takeuchi T, Naniwa T, Komatsuda A, Dobashi H, Amano K, Ogawa N, Murakawa Y, Hasegawa H, Hayashi T, Arimura Y, Isobe M, Harigai M; Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS). Clinical Characteristics and Treatment Outcomes of Patients With Newly Diagnosed Takayasu Arteritis in Japan During the First 2 Years of Treatment – A Nationwide Retrospective Cohort Study. Circ J 2024, 2024 Sep 12:CJ-24-0178, 被引用回数0
  137. Doi H, Ohmura K, Hashimoto M, Ueno K, Takase Y, Inaba R, Kozuki T, Iwasaki T, Taniguchi M, Tabuchi Y, Shirakashi M, Onizawa H, Tsuji H, Onishi A, Watanabe R, Kitagori K, Akizuki S, Murakami K, Nakashima R, Yoshifuji H, Yamamoto W, Itaya T, Uozumi R, Tanaka M, Morinobu A. Factors affecting discrepancies in disease activity evaluation between patients and physicians in systemic lupus erythematosus-The importance of symptoms such as fatigue. Lupus 2024, 33:1336-1344, 被引用回数0
  138. Sasai T, Nakashima R, Handa T, Yamano Y, Kondo Y, Matsuda S, Kotani T, Tomioka H, Tachikawa R, Tomii K, Tanizawa K, Nohda Y, Kogame T, Shirakashi M, Hiwa R, Tsuji H, Akizuki S, Yoshifuji H, Mimori T, Kabashima K, Morinobu A. Anti-interferon gamma-inducible protein 16 antibodies: Identification of a novel autoantigen in idiopathic interstitial pneumonia and its clinical characteristics based on a multicenter cohort study. Clin Immunol 2024, 2024 Sep 30:110372, 被引用回数0
  139. Kanda M, Nagahata K, Moriyama M, Takano KI, Kamekura R, Yoshifuji H, Tsuboi H, Yamamoto M, Umehara H, Umeda M, Sakamoto M, Maehara T, Inoue Y, Kubo S, Himi T, Origuchi T, Masaki Y, Mimori T, Dobashi H, Tanaka Y, Nakamura S, Takahashi H. The 2023 revised diagnostic criteria for IgG4-related dacryoadenitis and sialadenitis. Mod Rheumatol 2024, 2024 Oct 23:roae096, 被引用回数0
  140. Kambe N, Yamamoto M, Takemura K, Kagami SI, Kawahara Y, Yoshifuji H, Jo T, Izawa K, Nakamizo S, Inoue N, Ito T, Amino Y, Ibi Y, Morita S, Kanazawa N. Investigator-initiated, multi-center, single-arm, open-label study of the effectiveness of canakinumab in Japanese patients with Schnitzler syndrome. Allergol Int 2024, 2024 Dec 16:10001, 被引用回数0
  141. Fukumura M, Hiwa R, Yukawa S, Tsuchido Y, Yoshifuji H, Morinobu A. Uncommon concurrent pulmonary infections: Aspergillus fumigatus and Lomentospora prolificans in an Anti-MDA5 antibody-positive dermatomyositis patient. Med Mycol Case Rep 2024, 47:100689, 被引用回数0
  142. Tsuji H, Shirakashi M, Hiwa R, Akizuki S, Nakashima R, Onishi A, Yoshifuji H, Tanaka M, Morinobu A. Differences in the autoantibody phenotypes and long-term outcomes between juvenile- and adult-onset systemic sclerosis. Mod Rheumatol 2025, 2025 Jan 17:roaf005, 被引用回数0
  143. Otsuka M, Koga T, Sumiyoshi R, Fukui S, Kaneko Y, Shimizu T, Katsube A, Yano S, Masaki Y, Ide M, Yoshifuji H, Kitano M, Sato Y, Sawa N, Niiro H, Nakamura N, Fajgenbaum DC, van Rhee F, Kawakami A. Exploring the Clinical Diversity of Castleman Disease and TAFRO Syndrome: A Japanese Multicenter Study on Lymph Node Distribution Patterns. Am J Hematol 2025, 2025 Jan 25:27612, 被引用回数0
  144. Yoshifuji H, Ishii T, Morikawa K, Ohashi H, Yoshizawa K, Mihoya M, Nishikawa K, Nakaoka Y. A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Ustekinumab in Participants with Takayasu Arteritis. Rheumatol Adv Pract 2025, 9:rkaf013, ファーストオーサー, 被引用回数0                                                 《総説，欧文》（すべて査読あり）
  1. Mimori T, Imura Y, Nakashima R, Yoshifuji H. Autoantibodies in idiopathic inflammatory myopathy: an update on clinical and pathophysiological significance. Curr Opin Rheumatol 2007, 19:523-529, ラストオーサー, 被引用回数138
  2. Terao C, Yoshifuji H, Mimori T. Recent advances in Takayasu arteritis. Int J Rheum Dis 2014, 17:238-247, セカンドオーサー, 被引用回数90
  3. Yoshifuji H. Biomarkers and Autoantibodies of Interstitial Lung Disease with Idiopathic Inflammatory Myopathies. Clin Med Insights Circ Respir Pulm Med 2016, 9:141-146, ファーストオーサー, コレスポンディングオーサー, 被引用回数1
  4. Yoshifuji H. Pathophysiology of large vessel vasculitis and utility of interleukin-6 inhibition therapy. Mod Rheumatol 2019, 29:287-293, ファーストオーサー, コレスポンディングオーサー, 被引用回数37
  5. Isobe M, Amano K, Arimura Y, Ishizu A, Ito S, Kaname S, Kobayashi S, Komagata Y, Komuro I, Komori K, Takahashi K, Tanemoto K, Hasegawa H, Harigai M, Fujimoto S, Miyazaki T, Miyata T, Yamada H, Yoshida A, Wada T, Inoue Y, Uchida HA, Ota H, Okazaki T, Onimaru M, Kawakami T, Kinouchi R, Kurata A, Kosuge H, Sada KE, Shigematsu K, Suematsu E, Sueyoshi E, Sugihara T, Sugiyama H, Takeno M, Tamura N, Tsutsumino M, Dobashi H, Nakaoka Y, Nagasaka K, Maejima Y, Yoshifuji H, Watanabe Y, Ozaki S, Kimura T, Shigematsu H, Yamauchi-Takihara K, Murohara T, Momomura SI; JCS Joint Working Group. JCS 2017 Guideline on Management of Vasculitis Syndrome – Digest Version. Circ J 2020, 84:299-359, 被引用回数68
  6. Yoshifuji H, Terao C. Roles of cytotoxic lymphocytes and MIC/LILR families in pathophysiology of Takayasu arteritis. Inflamm Regen 2020, 40:9, ファーストオーサー, コレスポンディングオーサー, 被引用回数12
  7. Yoshifuji H, Umehara H. Glucocorticoids in the treatment of IgG4-related disease-Prospects for new international treatment guidelines. Mod Rheumatol 2023, 33:252-257, ファーストオーサー, コレスポンディングオーサー, 被引用回数8
  8. Yoshifuji H, Yomono K, Yamano Y, Kondoh Y, Yasuoka H. Role of rituximab in the treatment of systemic sclerosis: A literature review. Mod Rheumatol 2023, 33:1068-1077, ファーストオーサー, コレスポンディングオーサー, 被引用回数2
  9. Yamazaki S, Izawa K, Matsushita M, Moriichi A, Kishida D, Yoshifuji H, Yamaji K, Nishikomori R, Mori M, Miyamae T. Promoting awareness of terminology related to unmet medical needs in context of rheumatic diseases in Japan: a systematic review for evaluating unmet medical needs. Rheumatol Int 2023, 43:2021-2030, 被引用回数0